cohort · 2015 · en
Cardiometabolic Risks and Severity of Obesity in Children and Young Adults
Skinner A C, Perrin E M, Moss L A, Skelton J A
New England Journal of Medicine
Evidencia · Alta
Síntesis
NHANES analysis showing cardiometabolic risk (HDL, triglycerides, blood pressure, HbA1c) rises stepwise across severity-of-obesity classes II-III in U.S. youth.
Etapas
3-6, 6-12, 12-18
Dominios
endocrine, obesity, metabolism
Tags
severe-obesity · cardiometabolic-risk · NHANES · BMI-classes
Afirmaciones que citan esta fuente (1)
clm-obesity-endocrine-model
Childhood obesity is driven in significant part by hormonal mechanisms (hyperinsulinemia, leptin-melanocortin pathway dysfunction, hypothalamic dysregulation) rather than purely behavioral failure; treatment must move beyond willpower framing toward IHBLT, pharmacotherapy and, wh