review · 2012 · en
Prenatal Developmental Origins of Future Psychopathology: Mechanisms and Pathways
Monk C, Spicer J, Champagne FA
Annual Review of Clinical Psychology 8:391-415
Evidencia · AltaOpen Access
Síntesis
Integrative review of mechanisms (HPA axis, placental epigenetics, immune signaling) by which prenatal psychosocial exposures shape offspring psychopathology risk.
Etapas
0-1, transversal
Dominios
perinatal, epigenetics, mental-health, neuroscience
Tags
fetal-programming · prenatal-stress · epigenetics · DOHaD · review
Afirmaciones que citan esta fuente (1)
clm-epigenetic-programming-care-and-fetal
Maternal care in rodents programs offspring HPA-axis reactivity through DNA methylation of the glucocorticoid receptor (NR3C1); analogous, smaller-magnitude associations exist in humans between prenatal mood/stress and NR3C1/FKBP5 methylation in placenta or cord blood and neonata