review · 2006 · en
Childhood Obesity: Behavioral Aberration or Biochemical Drive? Reinterpreting the First Law of Thermodynamics
Lustig R H
Nature Clinical Practice Endocrinology & Metabolism
Evidencia · Seminal
Síntesis
Influential reframing of childhood obesity as a hormonally driven energy-storage state (hyperinsulinemia, leptin resistance) rather than purely behavioral, foundational to the endocrine model.
Etapas
3-6, 6-12, 12-18
Dominios
endocrine, obesity, metabolism
Tags
Lustig · hypothalamic-obesity · leptin-resistance · insulin · endocrine-model
Afirmaciones que citan esta fuente (1)
clm-obesity-endocrine-model
Childhood obesity is driven in significant part by hormonal mechanisms (hyperinsulinemia, leptin-melanocortin pathway dysfunction, hypothalamic dysregulation) rather than purely behavioral failure; treatment must move beyond willpower framing toward IHBLT, pharmacotherapy and, wh