review · 2016 · en
Causes, Diagnosis, and Treatment of Central Precocious Puberty
Latronico A C, Brito V N, Carel J-C
The Lancet Diabetes & Endocrinology
Evidencia · Alta
Síntesis
Comprehensive Lancet review covering genetic (MKRN3, KISS1R, DLK1) and environmental contributors to central precocious puberty and evidence-based management.
Etapas
3-6, 6-12
Dominios
endocrine, puberty, genetics
Tags
central-precocious-puberty · MKRN3 · kisspeptin · genetics · GnRH-analog
Afirmaciones que citan esta fuente (1)
clm-gnrh-precocious-puberty
Long-acting GnRH analogs are first-line therapy for central precocious puberty with progression and predicted adult-height compromise; evidence for psychosocial-only indications and idiopathic short stature is limited.