cohort · 2013 · en
The Roles of DNA Methylation of NR3C1 and 11β-HSD2 and Exposure to Maternal Mood Disorder in Utero on Newborn Neurobehavior
Conradt E, Lester BM, Appleton AA, Armstrong DA, Marsit CJ
Epigenetics 8(12):1321-1329
Evidencia · AltaOpen Access
Síntesis
Placental NR3C1 and 11β-HSD2 methylation mediates effects of maternal mood symptoms on neonatal neurobehavior, supporting the placenta as a fetal-programming organ.
Etapas
0-1
Dominios
perinatal, epigenetics, neuroscience
Tags
fetal-programming · placenta · NR3C1 · HSD11B2 · NICU-Network-Neurobehavioral-Scale · Conradt
Afirmaciones que citan esta fuente (1)
clm-epigenetic-programming-care-and-fetal
Maternal care in rodents programs offspring HPA-axis reactivity through DNA methylation of the glucocorticoid receptor (NR3C1); analogous, smaller-magnitude associations exist in humans between prenatal mood/stress and NR3C1/FKBP5 methylation in placenta or cord blood and neonata