meta-analysis · 2010 · en

Long-Term Safety of Recombinant Human Growth Hormone in Children

Bell J, Parker K L, Swinford R D, Hoffman A R, Maneatis T, Lippe B

Journal of Clinical Endocrinology & Metabolism

Evidencia · AltaOpen Access

DOI · 10.1210/jc.2009-1178

Síntesis

Genentech NCGS analysis (>50,000 patient-years) supporting overall favorable safety profile of rhGH in children, with rare adverse events including slipped capital femoral epiphysis and intracranial hypertension.

Etapas

3-6, 6-12, 12-18

Dominios

endocrine, growth